药品快速检测技术研究与应用(英文版) 化学工业出版社 下载 pdf 百度网盘 epub 免费 2025 电子书 mobi 在线

《药品快速检测技术的研究与应用（英文版）》为国家十三五重点出版物，对化学药品的快速检测理论与方法进行了详细的阐述，收录了化学药品近红外快速分析技术和HPLC的快速检测方法。本书由非常不错部门编写，内容原创。适用于从事药物质量监督与管理的人员。

Rapid Analysis of Chemical Drugs Using the Near-infrared Spectroscopic Technology

Chapter 1 NIR Spectrometer / 7

Classification and Characteristics of NIR Spectrometer / 7

Key Performance Indicators of NIR Spectroscopic Instrument / 11

Acquisition of NIR Spectrum / 16

NIR Spectrometer in Mobile lab / 17

Chapter 2 Introduction Near-infrared Analysis Methods / 20

Spectral Data Preprocessing Methods / 21

Qualitative Analysis Method / 25

Cluster Analysis / 31

Quantitative Analysis / 35

Conformity Test Analysis / 45

Correlation Coefficient Analysis / 49

Methods of Model Transfer / 52

Chapter 3 Application of NIR Methods in Drug Analysis / 58

Analysis of Antibiotics Using NIR Methods / 59

CASE STUDY 1 Establishment of Qualitative NIR Models for the Analysis of Cephalosporin Injection Powder Products / 61

CASE STUDY 2 Rapid Determination of Cefuroxime Sodium Content Using NIR Analysis / 66

CASE STUDY 3 Construction of a Universal NIR Model for Quantitative Analysis of Cefradine Capsules / 73

CASE STUDY 4 Development of a Universal NIR Model for Quantitative Analysis of Phenoxymethylpenicillin Potassium Tablets / 79

CASE STUDY 5 Universal NIR Models for the Quantitative Analysis of Ceftriaxone and Water Contents in Ceftriaxone Sodium Injection Products / 85

Analysis of Chemical Drugs Using NIR Methods / 96

CASE STUDY 6 Construction of a Quantitative Model for Simvastatin Tablets / 98

CASE STUDY 7 NIR Models for Quantitative Analysis of Aminosalicylate and Water Contents in Sodium Aminosalicylate Injections / 102

CASE STUDY 8 Rapid Analysis of Potassium Dehydroandrographolide Succinate Injection Using NIRDRS / 108

CASE STUDY 9 NIR Identification and Analysis of Compound Paracetamol and Amantadine Hydrochloride Tablets / 115

Application of NIR Spectroscopy in the Analysis of Traditional Chinese Medicines (TCM) / 120

CASE STUDY 10 Establishment of a Qualitative NIR Model for Cortex Magnoliae officinalis / 122

CASE STUDY 11 Analysis of Water Content in Liuwei Dihuang Pills Using NIR Spectroscopy / 129

CASE STUDY 12 Qualitative Analysis of Different Brands of Jianwei Xiaoshi Tablets Using NIR Spectroscopy / 131

CASE STUDY 13 Identification of Decoction Pieces of Common Yam Rhizome by NIR Method / 133

NIR Analysis of Illegal Additives in Medicinal Products / 143

CASE STUDY 14 Illegal Addition of Sildenafil Citrate into Chinese Patent Medicine / 144

CASE STUDY 15 Norfloxacin Addition in Lopermide Hydrochloride Capsules / 146

CASE STUDY 16 NIR Correlation Analysis of Illegal Added Phenformin Hydrochloride in Chinese Patent Medicines / 147

NIR Analysis of Liquid Formulations / 152

CASE STUDY 17 Construction NIR Quantitative Model for Glucose Injection / 154

Applications of NIR Methods on Mobile Laboratory Vehicles / 161

CASE STUDY 18 The Establishment and Application of Blank Models Used for Spectra Comparison / 164

CASE STUDY 19 Establishment and Application of the Characteristic Spectral Range Screening Method / 171

Chapter 4 Prospect of NIR Analysis Methods / 184

Development Prospect of NIR Analytical Instruments / 185

Prospect of the Application of NIR Analysis Method / 186

Prospect of NIR Analysis Methods being Listed in the National Drug Standards of Different Countries / 190

References / 192

Rapid HPLC Forensic Analysis of Chemical Medicines

Chapter 5 Basic Principles and Methods for Rapid HPLC Analysis / 202

Identification / 202

Content Determination / 202

Establishment and Validation of the Rapid HPLC Forensic Method / 203

Chapter 6 Applications of Rapid HPLC Analysis / 220

β-lactam Antibiotics / 221

Macrolide Antibiotics / 257

Quinolone Antibiotics / 276

Adrenocortical Hormone Drugs / 290

Sex Hormone Drugs / 306

Antidiabetic Drugs / 318

Calcium Channel Blockers / 332

Chapter 7 Progress of Rapid HPLC Analysis / 347

Establishment of Reference Database and Applications / 347

Rapid Analysis by LC-MS / 349

References / 353

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